Children of different ages often have digestive problems due to new foods, lack of enzymes, or for other reasons. To normalize the digestive tract, pediatricians often recommend a suspension of Motilium for children. The drug is an anti-vomiting agent that perfectly normalizes intestinal motility. In addition to the liquid form, it is also available in tablets.
The composition of the medication
The active ingredient in the Motilium suspension for children is domperidone, which produces an antiemetic effect and also normalizes the functioning of the entire digestive system. As auxiliary components, the composition also includes:
- carmellose sodium;
- sodium hydroxide;
- polysorbate;
- sorbitol;
- propyl parahydroxybenzoate;
- saccharinate;
- purified water;
- cellulose;
- methyl parahydroxybenzoate.
They additionally help cleanse the intestines, have a choleretic and detoxifying effect. Externally, the syrup is a white liquid of uniform consistency for oral use.
The product is packaged in brown glass bottles that are in cardboard boxes, which also includes instructions. For children, Motilium suspension is not the only form of the drug. Patients older than 5 years and weighing more than 35 kg can already take resorption tablets.
Pharmacology
The antiemetic effect of the drug is due to the fact that the main component of the composition is the opposite of dopamine. Also, the main substance enhances the production of prolactin. Some side effects characteristic of similar drugs are very rare, since domperidone is not able to pass through the circulatory system to nerve cells. Additionally, according to the instructions for use, the Motilium suspension for children is able to increase the sphincter tone, eliminating the difficulties in defecating patients with solid, semi-liquid and liquid feces. The drug does not stimulate the secretion of gastric juice.
Pharmacokinetics
The active active component of the composition is absorbed by the body very quickly and reaches its maximum concentration after 60 minutes after administration. If low acidity is observed in the baby’s stomach, then the absorption period slows down. When administered orally suspension for children, Motilium, up to 66% of the active substance is excreted in feces and up to 31% in urine. The rest is displayed in its original form. It is important to know that the active substance is not able to accumulate in the body and is metabolized in the liver and gastrointestinal tract. The half-life of the substance is 8 hours.
Recommendations for admission
According to the instructions, Motilium suspension for children can be used to treat patients from the first days of life, but only as directed by the pediatrician.
Frequent indications for the use of the drug are:
- food poisoning and intoxication;
- flatulence;
- heartburn;
- stomach ache;
- vomiting
- nausea;
- bloating;
- frequent spitting up in newborns;
- a feeling of fullness of the stomach and other disorders of the motor-evacuation functions of the digestive system.
Relief after the start of administration usually occurs on the second day. For newborns, the drug is also an effective remedy for colic, diarrhea, constipation, inflammation of the walls of the esophagus and rotavirus infections.
Admission Rules
How to take Motilium suspension for children? It is important to shake the entire contents of the vial well before dosing. After that, the cap with protection against accidental opening is unscrewed and the attached measuring syringe is inserted into the neck of the bottle.
After a set of the desired volume of suspension is added to it, the bottle closes, and the medicine is given to the baby. It is important to take the drug only before meals, because after eating its absorption slows down. To obtain the maximum therapeutic effect, the interval between taking the suspension and food should be 20-30 minutes.
Dosage
Only a pediatrician can accurately tell how much to give the child a suspension of Motilium, based on the individual characteristics of the patient’s body, his age, weight and diagnosis. Usually, 3-4 days of admission are sufficient to alleviate the condition, but with course treatment this period can also be a maximum mark of 28 days.
So, depending on the doctor’s testimony, children under 12 years of age and infants can be prescribed three times a day at 0.25-0.5 ml per kg of body weight. In this case, the maximum daily concentration of the substance should not be more than 2.4 ml / kg and should not exceed a volume of 80 ml. For babies over 12 years old and adults, it is necessary to drink 10-20 ml of suspension three times a day, so it is more advisable to use tablets. They are prescribed 1 piece 3 times a day.
The dosage of the suspension for children “Motilium” should be halved for patients with impaired renal function, since with such diagnoses the half-life of the active substance is doubled. In case of serious abnormalities in the liver, the medication should be completely abandoned.
Bans to use
An absolute contraindication to the suspension for children "Motilium" is personal intolerance to the body of any of the components of the composition of the product. In addition, it is forbidden to use the drug for treatment with pathologies in the liver, intestinal obstruction, suspected gastric bleeding, peptic ulcer tumors, tumors in the pituitary gland and cardiac abnormalities, kidney or myocardium in the treatment of vomiting. For tablets, an additional prohibition is the patient's weight less than 35 kg and intolerance to lactose, galactose and glucose.
It is forbidden to take the drug at the same time as Clarithromycin, Erythromycin, Telithromycin, Fluconazole, Amiodarone and other similar medicines.
With caution, treatment should be carried out for mild impairment of kidney function, heart failure, electrolyte imbalance and heart rhythm disturbances.
Side effects
According to reviews, Motilium suspension for children causes side effects very rarely. Their list is completely identical to other forms of release of the medication and is:
- From the side of the nervous system - drowsiness, disturbances in muscle tone, headaches, cramps, tremors and so on.
- From the digestive system - dry mouth, intestinal cramps, impaired appetite, diarrhea, thirst, constipation and so on.
- From the endocrine system - galactorrhea, gynecomastia, amenorrhea, increased prolactin levels.
- Nervous system - agitation, nervousness.
- The immune system - allergic and anaphylactic reactions.
Overdose
Exceeding the recommended dose for therapy is manifested by pronounced side symptoms. Neurological disorders can give a particularly strong reaction.
Treatment of various manifestations is symptomatic. General recommendations are only to stop taking "Motilium" and the appointment of a sorbent. In severe cases, gastric lavage may be necessary.
During pregnancy
Suspension for children "Motilium" very often, doctors advise women to take during gestation. In fact, at the moment there is not enough data on the safety of the drug during pregnancy, so drink the suspension only if the benefit to the mother justifies the possible risks to the fetus.
A similar situation exists with the lactation period. It is proved that the active substance of the composition can penetrate through the milk to the baby, however, its negative or positive effects are unknown. If treatment is necessary, it is recommended to temporarily stop breastfeeding.
special instructions
In the presence of sorbitol intolerance, treatment with the drug should not be carried out. Also, if necessary, simultaneous treatment with antisecretory or antacid drugs, the latter should be taken separately, at least after meals.
The drug does not affect the ability to drive mechanisms or vehicles.
The dosage for newborns should be calculated especially accurately, since their nervous system and metabolic functions are still poorly developed, and the drug can provoke severe neurological disorders. Of course, other possible causes of the appearance of such disorders should be considered.
Some studies have shown that domperidone is able to provoke ventricular arrhythmias, which is the cause of coronary death. Such reactions really have a place to be, but only in patients over 60 years of age and taking the drug in high doses. For children of any age and adults there is no such danger.
Drug interaction
The therapeutic effect of Motilium is completely neutralized while being taken with anticholinergics.
If you take sodium bicarbonate, cimetidine, antisecretory or antacid drugs in parallel with the suspension, then its bioavailability is markedly reduced. It is forbidden to take Motilium together with Erythromycin and Ketoconazole, as this provokes a change in the electrocardiogram.
Medicines such as Fluconazole, Ampenavir, Clarithromycin, and others can enhance the effect of the drug in question, so a dose adjustment may be necessary. The simultaneous administration of digoxin and paracetamol with a suspension does not affect the work of medications.
It is believed that the drug could affect the absorption of other enteric-coated oral medicines.
You can take Motilium along with antipsychotics and drugs, the side effects of which are vomiting, nausea and other digestive disorders. Suspension stops undesirable symptoms, while not affecting the main and action.
Reviews
Many parents have a positive attitude to the suspension for children Motilium. Reviews with vomiting indicate that the drug copes with unpleasant symptoms on the second day of admission. It is also very effective in the treatment of rotavirus infections.
The complex treatment of frequent burping, belching and colic in babies helps to completely get rid of them in a few days. The suspension helped many future mothers to get rid of constant nausea and vomiting during toxicosis. Many consider the absence of side effects as positive moments while taking the drug, although their list is quite extensive. Good reviews are expressed by adult patients, whom the tool helps to cope with regular digestive disorders, feelings of heaviness and bloating after a heavy meal.
Among the shortcomings, only the high cost of the medication should be noted. Depending on the region of sale and the margin of the distributor, the price of a suspension may vary within 600 rubles per bottle of 100 ml. In the form of tablets "Motilium" can be purchased a little cheaper. A pack of 30 pills for resorption will cost about 550-650 rubles, but if necessary, you can buy a pack of only 10 tablets for 400 rubles. For oral use, tablets also cost 550-650 rubles for 30 pieces.
Analogues of the drug
Cheap analogues of Motilium suspension for children can be found in every pharmacy. Most often, for infants to eliminate similar symptoms, pediatricians can prescribe Domperidone, the price of which ranges from only 80-200 rubles. The drug differs in the absence of additional components that enhance the effect of domperidone itself. To eliminate colic, intestinal cramps, vomiting, regurgitation and nausea, you can also use drugs such as Maalox or Ganaton. They are also allowed to be used in the treatment of children, and medicines can be purchased for about 300 rubles.
Below are other structural analogues of Motilium suspension for children:
- Motilak;
- "Domet";
- "Motonium";
- Passasics;
- "Motinorm";
- Motizheks;
- Domstal and others.
It is important to remember that only a specialist has the right to carry out the replacement of the drug with another, even with the same composition.
Storage
Despite the safe cap with a safety guard against accidental opening, keep the bottle with the medication out of the reach of children. The shelf life of the drug in suspension and tablets for oral use is 5 years, and in soluble tablets - 3 years. The temperature during storage should be in the range of 15-30 0 C. If the storage requirements are not met, then taking the product is strictly prohibited. You can not use the medicine after the expiration date.