It happens that the doctor prescribes a drug, for example, Fraxiparin, in the annotation of which it is indicated that it is not recommended to use it during pregnancy . It is natural that expectant mothers are embraced by excitement. Is it safe to take fraxiparin with pregnancy?
The new generation drug product Fraxiparin is a derivative of the heparin known to many, but is more effective and safe. The main active ingredient of the drug is calcium nadroparin. Immediate prolonged antithrombotic effect is the main advantage of the drug.
In what cases is Fraxiparin prescribed during pregnancy ?
This drug is an anticoagulant. During pregnancy, it is used to prevent the formation of blood clots and prevent spasm of blood vessels, which can affect both the process of the embryo joining the uterine wall and changes in the formation of the placenta.
Many women are advised to take Fraxiparin during pregnancy during the entire period in order to prevent serious violations of the placenta. It is also prescribed in the presence of signs of fetal hypoxia and chronic hypertension.
The drug is prescribed only after all the necessary blood tests for coagulation and anticoagulability. Further treatment should occur under the supervision of a physician.
Fraxiparin - instructions for use
Fraxiparin is available as a solution, which is injected into the subcutaneous tissue in the abdomen. In this case, the needle should be located perpendicular to the skin fold, which must be maintained during the entire time of injection. The course of treatment and dosage should be indicated by the attending physician.
Specialists who prescribe the drug claim that Fraxiparin is completely safe for expectant mothers, because there is no threat of its penetration through the placenta.
But still, it is worth taking into account the existing contraindications of the drug, which say that the drug can not be used for ulcerative exacerbations of the duodenum and stomach, serious violations of the kidneys or liver, hypertension, as well as for any other diseases that increase the risk of bleeding. It is worth considering the individual intolerance of this drug.
Side effects and overdose
Taking the drug can be the cause of a number of side effects: temporary and fleeting liver dysfunction, bleeding and decreased platelet count in the blood, redness and itching in the injection area, Quincke's edema, urticaria, and rarely anaphylactic shock.
A sign of an overdose is bleeding. With minor bleeding, the next injection should be delayed. In more serious cases, intravenous administration of protamine sulfate is required, which neutralizes the effect of Fraxiparin.
Fraxiparin - analogues of the drug
Fraxiparin has many analogues that are part of the same pharmacological subgroup and are close in their mechanism of action:
- Angioflux (capsules);
- Angioflux (solution for intramuscular and intravenous administration);
- Antithromin 3 human lyophilisate (solution for infusion);
- Vesel Douay F (capsules or solution for intramuscular and intravenous administration);
- Hemapaxan (solution for subcutaneous injection) ;
- Heparin (amphora powder);
- Heparin (for subcutaneous injection and intravenous administration);
- Heparin Sandoz (solution for subcutaneous injection);
- Heparin-Ferein (for subcutaneous and intravenous administration);
- Heparin sodium (for subcutaneous and intravenous administration);
- Clexane (solution for subcutaneous injection);
- Piyavit (capsules);
- Fragmin (for subcutaneous and intravenous administration);
- Zibor 2500 or 3500 (for subcutaneous injection);
- The leech is medical.
The above medicines, although similar in composition and effect to the drug Fraxiparin, should be prescribed only by a doctor during pregnancy.