During the period of bearing a baby, a woman can often experience an exacerbation of her chronic diseases. This is facilitated by a changing hormonal background and weakened immunity. Gastrointestinal problems are not uncommon among women in position. However, what drugs are acceptable for relieving exacerbation and unpleasant symptoms during gestation? In particular, is it possible to drink De Nol during pregnancy? After all, this drug protects the gastric mucosa well. Let's get it together.
The purpose of the drug
De-Nol is an antiulcer drug. It has a bactericidal effect. Helicobacter pylori bacteria are susceptible to its influence, which are known for causing diseases such as gastritis, gastroduodenitis and gastric ulcer.
The drug performs a protective function for the mucous membrane of the stomach and duodenum. This prevents bacteria from damaging the tissues of the stomach and forming ulcers. However, the appointment of "De Nola" during pregnancy has its limitations.
Composition "De Nola"
The composition of the drug includes bismuth tripotassium dicitrate. One tablet contains 120 mg of this active substance. In addition to it, the medication contains the following excipients:
- ammonium and potassium citrates;
- povidone K30;
- polacriline potassium;
- magnesium stearate;
- corn starch;
- macrogol 6000;
- hydroxypropyl methylcellulose.
“De-Nol” during pregnancy can be replaced by other, more gentle plant-based drugs that protect the mucous membrane and its affected areas, preventing stomach acid from further harming the mucosa.
Release form
The drug is available in tablets. Externally, they have the following characteristics: round, biconvex, white or cream, mostly odorless, on the one hand there is the inscription gbr 152, on the other - a square with discontinuous sides and rounded corners.
Sale "De Nol" in cardboard packaging. Inside there are 7 or 14 blisters containing 8 tablets. Also in each package is an instruction for use. However, no matter what is written in it, is it possible during pregnancy "De-Nol" or not, only your doctor determines. Self-medication in this case is prohibited.
Features of the reception "De Nola"
During pregnancy, De-Nol has special instructions about the reception, which are determined by the doctor prescribing this drug for you. However, in addition to this, there are a number of features related to this drug. For example, you should not take the drug for more than two months without a break. You also need to strictly adhere to the prescribed dosages. Their increase or decrease can have negative consequences for the body.
Since bismuth is contained in this medication, then while taking De-Nol, you should refuse to take other drugs, which also include this component. After you drink a course of this drug, it is recommended to take a blood test. This is necessary in order to determine the concentration of the active substance and prevent intoxication.
During the reception of "De-Nola" may change the color of feces to a darker, up to black. This is due to the formation of bismuth sulfide. In addition, you can observe a darkening of the tongue, but it is usually not as pronounced as the darkening of feces.
Dosage and administration
How to take the drug, your doctor will prescribe for you, given the severity of your condition. Usually, the following dosages are indicated in the instructions for use.
- Adults and children over 12 years of age - 1 tablet 4 times a day half an hour before meals and at night or 2 tablets 2 times a day half an hour before meals.
- Children from 8 to 12 years old - 1 tablet 2 times a day half an hour before meals.
- Children from 4 to 8 years old - 8 mg of the drug per 1 kg of weight per day. The daily dosage is divided into 2 times and given half an hour before meals.
Drink the tablets with a little water. The duration of the course of treatment is also determined by a specialist. But usually it is no more than 1-2 months. After which a break is required.
As for the reception of "De-Nola" during pregnancy, then only the doctor determines the dosage and method of use.
The drug is also recommended to be taken in combination with antibacterial drugs that inhibit the activity of the Helicobacter pylori bacteria.
Complex therapy
Very often, together with De-Nol, antimicrobials are prescribed. Among them:
- Clarithromycin;
- Amoclicillin;
- Metranidazole
- "Tetracycline";
- "Furazolidone."
After the appointment, the drugs are taken from a week to 10 days. During this time, bacteria are eliminated from the body. Further, as a maintenance therapy and to prevent relapse continue to take only "De-Nola". This usually lasts up to one, maximum two months.
After the course of treatment is completed, a break is made for at least 2 months. During this period, you can not take drugs that contain bismuth in their composition. Otherwise, intoxication of the body may occur.
It is not recommended to drink tablets with milk or fruit juice. Only clean water (a small amount) is suitable for this.
As for the use of alcohol while taking the drug, there is no data on their interaction. But judging logically, what kind of alcohol can be in the treatment of peptic ulcer of the gastrointestinal tract?
"De-Nol" during pregnancy, as we have said, is contraindicated. And this is not to mention complex therapy in conjunction with antimicrobials or, moreover, antibiotics. Many analogues of the drug are also not allowed for use by pregnant and lactating women. Therefore, you should contact a specialist to select an alternative solution in this case.
Advantages and disadvantages of the drug
Like any drug, De-Nola has its pros and cons. The benefits of the medication are:
- lack of resistance;
- has a strong antimicrobial effect;
- has a wide range of effects;
- high-speed drug;
- an improved drug, gives less side effects during its use;
- the availability of the drug is sold in all pharmacies.
Among the shortcomings are noted:
- fairly high price;
- prescription leave only;
- "De-Nol" is contraindicated during pregnancy, as it has a negative effect on the fetus.
Indications for use
De-Nol is prescribed for those patients whose gastrointestinal tract disorders are caused by the pathological effects of Helicobacter pylori. These diseases include:
- chronic erosive gastritis in the acute stage;
- an ulcer of the stomach and intestines;
- gastroduodenitis in the acute stage;
- irritable bowel syndrome accompanied by diarrhea.
If you have one of the above symptoms, and you are wondering if you can drink De Nol during pregnancy, then the answer to this question, unfortunately, will be no. To combat such conditions, a pregnant woman will have to resort to other, less aggressive means.
Who Should Not Take De Nol?
As we have already mentioned, the drug is contraindicated in women in position. "De-Nol" during pregnancy in the early and late stages is able to penetrate the placental barrier, and, therefore, harm the health of the fetus.
In addition, in the instructions for use, we find the following contraindications:
- hypersensitivity to bismuth;
- impaired kidney function;
- disturbances in the liver;
- pregnancy period;
- lactation period;
- children under 4 years old.
Effect on the fetus
"De-Nol" is not prescribed for pregnant women, since it is able to penetrate the blood and tissues. The active substance of the drug is quite aggressive and easily penetrates the nervous system of the child. The drug causes mutations in the central nervous system of the fetus, in particular, disrupts the development of the neural tube.
Since the neural tube is one of the very first formations that are laid in the embryo, taking De-Nola during pregnancy in the early stages is strictly prohibited. Under the negative influence of the drug, the fetal nervous system will initially develop defectively. And this entails all kinds of malformations at the genetic level.
If you have been prescribed the drug during lactation, then during the treatment it is necessary to stop breastfeeding.
Price and analogues
The price category "De Nola" is quite high - from 510 rubles to 1060 rubles. For various reasons, people resort to using analogues. Someone does not fit the drug itself, someone does not like the price. Here are a number of similar drugs:
- Novosimbol is completely analogous to De Nol, only it is a Russian-made drug, unlike De Nol, which is produced in the Netherlands. This drug can be used for preventive purposes, as well as in conjunction with antibiotics. However, it should also not be taken for longer than 2 months and given to children under 4 years of age. Price: from 270 rubles to 750 rubles.
- "Parit" is a Belgian drug that has an antisecretory effect. The active substance is different for him - rabeprazole sodium. It is mainly used for gastrointestinal ulcers. It is convenient in that it is enough to take it once a day. However, it is not suitable for the treatment of children under 12 years of age, causes a large number of side effects and is prohibited for pregnant and lactating women. Price: from 825 rubles to 4000 rubles.
- "Venter" - the drug is made in Slovenia. The active substance is sucralfate. When taking this drug, side effects are extremely rare. But the drug should be taken only after meals, and it is not approved for the treatment of children under 4 years old. Price: from 235 rubles to 295 rubles.
- "Omez D" is an Indian drug, available in capsules. The active substance is dompiridone and omeprazole in equal quantities. It is intended mainly for the treatment of gastrointestinal tract disorders and gastroesophageal reflux. Take enough 2 times a day. It is suitable for the treatment of peptic ulcer and facilitates the process of bowel movement. However, "Omez D" can disrupt the hormonal background and is not used to treat children. Price: from 80 rubles to 330 rubles.
- Nolpaza is also a drug from Slovenia. Reduces the secretion of the gastric glands, thereby affecting the healing process. Suitable for the prevention of gastrointestinal diseases. The intake of this drug should be monitored by a doctor, especially with prolonged use. It can cause numerous adverse reactions and is prohibited for use by children under 18 years of age. Price: from 135 rubles to 670 rubles.
- Omeprazole is the most affordable analogue of De-Nola, a Russian-made product. The active substance of the tablets is omeprazole. It can be taken with meals. After taking the drug, secretory function is quickly restored. But it should not be taken by pregnant, lactating and children. Price: from 30 rubles to 70 rubles.